Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 8/20 | 0.55 |
| ▸ | PRKACA | P17612 | 5/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.50 |
| ▸ | AKT2 | P31751 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | AKT3 | Q9Y243 | 3/20 | 0.50 |
| ▸ | PRKACG | P22612 | 3/20 | 0.50 |
| ▸ | PRKACB | P22694 | 3/20 | 0.50 |
| ▸ | PRKCG | P05129 | 3/20 | 0.50 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.50 |
| ▸ | AKT1 | P31749 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.50 |
| ▸ | PRKCB | P05771 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9483550 | 0.86 | FLT3 (0.53) | FLT3PRKACAROCK2AKT2MAPK1 | |
| SCHEMBL9483554 | 0.86 | FLT3 (0.53) | FLT3PRKACAROCK2AKT2MAPK1 | |
| SCHEMBL9484549 | 0.82 | FLT3 (0.79) | FLT3PRKACAROCK2AKT2MAPK1 | |
| SCHEMBL9484535 | 0.82 | FLT3 (0.79) | FLT3PRKACAROCK2AKT2MAPK1 | |
| SCHEMBL9634900 | 0.79 | FLT3 (0.64) | FLT3PRKACAROCK2AKT2MAPK1 | |
| SCHEMBL9484230 | 0.78 | FLT3 (0.51) | FLT3PRKACAROCK2AKT2MAPK1 | |
| SCHEMBL9484225 | 0.78 | FLT3 (0.51) | FLT3PRKACAROCK2AKT2MAPK1 | |
| SCHEMBL9484329 | 0.78 | FLT3 (0.63) | FLT3PRKACAROCK2AKT2MAPK1 | |
| SCHEMBL9484331 | 0.78 | FLT3 (0.63) | FLT3PRKACAROCK2AKT2MAPK1 | |
| SCHEMBL9483657 | 0.77 | FLT3 (0.59) | FLT3PRKACAROCK2AKT2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6293730-A | — | — | None | — | — | JP | disclosed |
| JP-H06293730-A | TOLUIDINE DERIVATIVE AND ITS PRODUCTION | HIDAKA HIROYOSHI | 1994-10-21 | — | — | JP | disclosed |