Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408203 | 1.00 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL1763000 | 0.86 | GAA (0.47) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL13155816 | 0.86 | GAA (0.47) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL3108045 | 0.86 | GAA (0.47) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL3108052 | 0.86 | GAA (0.47) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL12593429 | 0.85 | MGAM (0.38) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL11363678 | 0.83 | MGAM (0.44) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL11363677 | 0.83 | MGAM (0.44) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL6246474 | 0.79 | GAA (0.52) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL6246476 | 0.79 | GAA (0.52) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609371-A1 | THIENOPYRAZINE-2,3-DIONES AND THEIR PREPARATION AND USE. | NOVO NORDISK AS (DK) | 1994-08-10 | — | — | EP | disclosed |
| WO-1993008197-A1 | THIENOPYRAZINE-2,3-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-04-29 | — | — | WO | disclosed |