Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 17/20 | 0.47 |
| ▸ | USP5 | P45974 | 1/20 | 0.43 |
| ▸ | USP14 | P54578 | 1/20 | 0.43 |
| ▸ | USP7 | Q93009 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409330 | 0.91 | GRM2 (0.58) | GRM2SIGMAR1 | |
| SCHEMBL8948618 | 0.88 | GRM2 (0.53) | GRM2SIGMAR1 | |
| SCHEMBL8311049 | 0.88 | GRM2 (0.53) | GRM2SIGMAR1 | |
| SCHEMBL8948494 | 0.88 | GRM2 (0.53) | GRM2SIGMAR1 | |
| SCHEMBL8310660 | 0.86 | GRM2 (0.51) | GRM2SIGMAR1 | |
| SCHEMBL8313964 | 0.84 | GRM2 (0.54) | GRM2SIGMAR1 | |
| SCHEMBL8948770 | 0.84 | GRM2 (0.52) | GRM2SIGMAR1 | |
| SCHEMBL8948767 | 0.83 | GRM2 (0.48) | GRM2SIGMAR1 | |
| SCHEMBL8948784 | 0.82 | GRM2 (0.53) | GRM2SIGMAR1 | |
| SCHEMBL8948675 | 0.82 | GRM2 (0.53) | GRM2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623615-A1 | Adhesion-receptor antagonists | MERCK PATENT GmbH (DE) | 1994-11-09 | — | — | EP | disclosed |