SCHEMBL9409348

SCHEMBL9409348

CSc1ncc(N)c(N)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HASPIN Q8TF76 1/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
HSP90AB1 P08238 2/20 0.35
ABCB1 P08183 2/20 0.35
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 3/20 0.33
NTRK1 P04629 1/20 0.33
HSP90AA1 P07900 1/20 0.32
UHRF1 Q96T88 1/20 0.32
POLB P06746 1/20 0.32
RAB9A P51151 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
GAA P10253 1/20 0.32
TSHR P16473 1/20 0.32
HTT P42858 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
LMNA P02545 1/20 0.32
NUDT1 P36639 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5314141 0.80 HSP90AB1 (0.39) HASPINMEN1KMT2AHSP90AB1ABCB1
SCHEMBL10261190 0.80 HASPIN (0.38) HASPINMEN1KMT2AHSP90AB1ALDH1A1
SCHEMBL6473545 0.80 HSP90AB1 (0.39) HASPINMEN1KMT2AHSP90AB1ALDH1A1
SCHEMBL19725081 0.78 MEN1 (0.44) HASPINMEN1KMT2AHSP90AB1ALDH1A1
SCHEMBL22057624 0.78 KMT2A (0.53) HASPINMEN1KMT2AALDH1A1KDM4E
Hydrochloric Acid SCHEMBL27478819 0.78 AHR (0.38) HASPINMEN1KMT2AHSP90AB1ALDH1A1
SCHEMBL2039264 0.78 MEN1 (0.41) HASPINMEN1KMT2AHSP90AB1ABCB1
SCHEMBL18426678 0.78 HASPIN (0.37) HASPINMEN1KMT2AHSP90AB1ABCB1
SCHEMBL18232261 0.78 HASPIN (0.37) HASPINMEN1KMT2AHSP90AB1ABCB1
SCHEMBL1492552 0.78 HASPIN (0.37) HASPINMEN1KMT2AHSP90AB1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0584797-A2 Novel cephalosporin compounds and processes for the preparation thereof LUCKY LTD. (KR) 1994-03-02 EP disclosed