Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.62 |
| ▸ | FNTB | P49356 | 5/20 | 0.62 |
| ▸ | ACE | P12821 | 3/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.54 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409873 | 1.00 | FNTA (0.62) | FNTAFNTBACEOPRD1PGGT1B | |
| SCHEMBL9409859 | 1.00 | FNTA (0.62) | FNTAFNTBACEOPRD1PGGT1B | |
| SCHEMBL9409955 | 0.92 | FNTA (0.60) | FNTAFNTBOPRD1PGGT1BAGTR1 | |
| SCHEMBL9409972 | 0.92 | FNTA (0.60) | FNTAFNTBOPRD1PGGT1BAGTR1 | |
| SCHEMBL9409964 | 0.92 | FNTA (0.60) | FNTAFNTBOPRD1PGGT1BAGTR1 | |
| SCHEMBL9409925 | 0.90 | FNTA (0.62) | FNTAFNTBACEOPRD1PGGT1B | |
| SCHEMBL9410018 | 0.90 | FNTA (0.62) | FNTAFNTBACEOPRD1PGGT1B | |
| SCHEMBL9409945 | 0.90 | FNTA (0.62) | FNTAFNTBACEOPRD1PGGT1B | |
| SCHEMBL9409937 | 0.90 | FNTA (0.62) | FNTAFNTBACEOPRD1PGGT1B | |
| SCHEMBL9410086 | 0.89 | FNTA (0.77) | FNTAFNTBOPRD1PGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618221-A2 | Heterocyclic inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-10-05 | — | — | EP | claimed |
| EP-0618221-A2 | Heterocyclic inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-10-05 | — | — | EP | disclosed |