Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | PREP | P48147 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409960 | 1.00 | ACE (0.37) | ACEDPP4DPP8DPP7PREP | |
| SCHEMBL8634381 | 0.75 | PREP (0.34) | ACEPREP | |
| SCHEMBL8634379 | 0.75 | PREP (0.34) | ACEPREP | |
| SCHEMBL1652402 | 0.70 | ACE (0.54) | ACEDPP4DPP8DPP7PREP | |
| SCHEMBL9409947 | 0.70 | ACE (0.54) | ACEDPP4DPP8DPP7PREP | |
| SCHEMBL7366403 | 0.69 | NPC1 (0.48) | PREP | |
| SCHEMBL15372544 | 0.67 | — | — | |
| SCHEMBL25177843 | 0.67 | — | — | |
| SCHEMBL7445466 | 0.67 | — | — | |
| SCHEMBL7447275 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023166039-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR Lasß | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-09-07 | — | — | WO | disclosed |
| EP-0618221-A2 | Heterocyclic inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-10-05 | — | — | EP | disclosed |