Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.81 |
| ▸ | TP53 | P04637 | 3/20 | 0.81 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 5/20 | 0.70 |
| ▸ | MEN1 | O00255 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.70 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.70 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.70 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.70 |
| ▸ | HTR1A | P08908 | 1/20 | 0.70 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.70 |
| ▸ | DRD2 | P14416 | 1/20 | 0.70 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.70 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9410177 | 0.99 | MAPT (0.80) | MAPTTP53HSP90AB1ALDH1A1LMNA | |
| SCHEMBL9410209 | 0.90 | MAPT (1.00) | MAPTTP53HSP90AB1ALDH1A1LMNA | |
| SCHEMBL9410198 | 0.90 | MAPT (0.82) | MAPTTP53HSP90AB1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9410218 | 0.89 | MAPT (0.98) | MAPTTP53HSP90AB1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9410223 | 0.89 | MAPT (0.81) | MAPTTP53HSP90AB1ALDH1A1LMNA | |
| SCHEMBL7708516 | 0.85 | MAPT (0.70) | MAPTTP53HSP90AB1ALDH1A1LMNA | |
| SCHEMBL8611873 | 0.84 | MAPT (0.73) | MAPTTP53HSP90AB1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7711145 | 0.84 | MAPT (0.69) | MAPTTP53HSP90AB1ALDH1A1LMNA | |
| SCHEMBL17313697 | 0.84 | KCNH2 (0.78) | MAPTTP53HSP90AB1ALDH1A1LMNA | |
| SCHEMBL7711545 | 0.83 | MAPT (0.71) | MAPTTP53HSP90AB1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611748-A1 | Propanolamine derivatives and their use as hypotensive or antiglaucoma agents | Senju Pharmaceutical Co., Ltd. (JP) | 1994-08-24 | — | — | EP | claimed |