Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.45 |
| ▸ | HTR3B | O95264 | 4/20 | 0.45 |
| ▸ | HTR3A | P46098 | 4/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411988 | 0.90 | CHRNA7 (0.51) | CHRNA7CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL5987493 | 0.88 | TP53 (0.51) | MEN1NPC1RAB9AKMT2ACHRNA7 | |
| SCHEMBL6153372 | 0.88 | TP53 (0.51) | MEN1NPC1RAB9AKMT2ACHRNA7 | |
| SCHEMBL5987496 | 0.88 | TP53 (0.51) | MEN1NPC1RAB9AKMT2ACHRNA7 | |
| SCHEMBL6153370 | 0.88 | TP53 (0.51) | MEN1NPC1RAB9AKMT2ACHRNA7 | |
| SCHEMBL374845 | 0.86 | CHRNA7 (0.59) | CHRNA7CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL6153288 | 0.86 | CHRNA7 (0.59) | CHRNA7CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL6153668 | 0.86 | CHRNA7 (0.59) | CHRNA7CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL374846 | 0.86 | CHRNA7 (0.59) | CHRNA7CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL6153661 | 0.86 | CHRNA7 (0.59) | CHRNA7CHRM2CHRM1CHRM3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581165-A2 | Acrylamide derivatives as antirussive agent | DOMPE' FARMACEUTICI S.p.A. (IT) | 1994-02-02 | — | — | EP | disclosed |