SCHEMBL94124

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL94587	0.78	NPC1 (0.71)	HDAC1ALOX15MAPTSMN1; SMN2ALDH1A1
	SCHEMBL18147885	0.77	SMN1; SMN2 (0.78)	HDAC1ALOX15MAPTSMN1; SMN2ALDH1A1
	SCHEMBL21626410	0.75	MAPT (0.49)	HDAC1ALOX15PYGLKCNMA1MAPT
	SCHEMBL9834269	0.75	KMT2A (0.56)	ALOX15PYGLMAPTNPSR1KMT2A
	SCHEMBL18146518	0.74	KMT2A (0.62)	PYGLMAPTSMN1; SMN2ALDH1A1NPC1
	SCHEMBL30492552	0.74	MAPT (0.78)	HDAC1MAPTSMN1; SMN2ALDH1A1NPC1
	SCHEMBL866785	0.74	MAPT (0.78)	HDAC1MAPTSMN1; SMN2ALDH1A1NPC1
	SCHEMBL30739586	0.74	HDAC1 (0.75)	HDAC1SMN1; SMN2NPC1RAB9AMEN1
	SCHEMBL6748058	0.74	PTPN1 (0.73)	SMN1; SMN2NPC1RAB9AMEN1KMT2A
	SCHEMBL30117876	0.74	CA1 (0.57)	ALOX15PYGLSMN1; SMN2KDM4ENPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.