Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 9/20 | 0.54 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28355828 | 0.81 | CYP17A1 (0.55) | CYP17A1CYP26A1ADRB2ADRB1ADRB3 | |
| SCHEMBL12781727 | 0.78 | CYP17A1 (0.55) | CYP17A1CYP26A1ADRB2ADRB1ADRB3 | |
| SCHEMBL10965559 | 0.78 | CYP11B1 (0.57) | CYP17A1CYP26A1ADRB2ADRB1ADRB3 | |
| SCHEMBL3170149 | 0.76 | CYP17A1 (0.50) | CYP17A1CYP26A1ADRB2ADRB1ADRB3 | |
| SCHEMBL9323996 | 0.75 | CYP17A1 (0.49) | CYP17A1CYP26A1ADRB2ADRB1ADRB3 | |
| SCHEMBL29456769 | 0.75 | CYP17A1 (0.49) | CYP17A1CYP26A1ADRB2ADRB1ADRB3 | |
| SCHEMBL28139868 | 0.75 | CYP17A1 (0.49) | CYP17A1CYP26A1ADRB2ADRB1ADRB3 | |
| SCHEMBL23234111 | 0.75 | CYP17A1 (0.81) | CYP17A1CYP26A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL27784193 | 0.75 | CYP17A1 (0.81) | CYP17A1CYP26A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL4043257 | 0.75 | CYP17A1 (0.81) | CYP17A1CYP26A1CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600315-A1 | Use of bentylimidazolyl derivatives as microbiocides for protecting materials | BAYER AG (DE) | 1994-06-08 | — | — | EP | disclosed |
| EP-0066144-B1 | BENZYLAZOLE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1986-02-19 | — | — | EP | disclosed |
| US-4430331-A | Antiarrhytmic benzylimidazole | SHIONOGI & CO., LTD. (JP) | 1984-02-07 | — | — | US | disclosed |