Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 11/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8302569 | 0.90 | MAPT (0.42) | GRIA2PDE3BPDE3APDE4APDE4B | |
| SCHEMBL8718589 | 0.84 | GRIA2 (0.43) | GRIA2PDE3BPDE3APDE4APDE4B | |
| SCHEMBL8302688 | 0.82 | GRIA2 (0.37) | GRIA2PDE3BPDE3APDE4APDE4B | |
| SCHEMBL8302588 | 0.80 | PDE3B (0.44) | GRIA2PDE3BPDE3APDE4APDE4B | |
| Bromide SCHEMBL9235635 | 0.79 | PDE3B (0.43) | GRIA2PDE3BPDE3APDE4APDE4B | |
| SCHEMBL8302585 | 0.75 | MAPT (0.46) | GRIA2PDE3BPDE3APDE4APDE4B | |
| SCHEMBL8307491 | 0.75 | GRIA2 (0.45) | GRIA2PDE3BPDE3APDE4APDE4B | |
| SCHEMBL8300942 | 0.71 | PDE3B (0.44) | GRIA2PDE3BPDE3APDE4APDE4B | |
| SCHEMBL8300364 | 0.71 | TBXA2R (0.45) | GRIA2PDE3BPDE3APDE4APDE4B | |
| SCHEMBL8307154 | 0.70 | HDAC8 (0.52) | GRIA2PDE3BPDE3APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579059-A1 | Pyridazinone derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |