Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9415764 | 1.00 | POLB (0.56) | POLBABCB1RAB9AMEN1KMT2A | |
| SCHEMBL9415767 | 1.00 | POLB (0.56) | POLBABCB1RAB9AMEN1KMT2A | |
| SCHEMBL9415393 | 1.00 | POLB (0.56) | POLBABCB1RAB9AMEN1KMT2A | |
| SCHEMBL9414795 | 0.92 | POLB (0.61) | POLBABCB1RAB9AMEN1KMT2A | |
| SCHEMBL9414791 | 0.92 | POLB (0.61) | POLBABCB1RAB9AMEN1KMT2A | |
| SCHEMBL9415247 | 0.92 | POLB (0.61) | POLBABCB1RAB9AMEN1KMT2A | |
| SCHEMBL9415244 | 0.92 | POLB (0.61) | POLBABCB1RAB9AMEN1KMT2A | |
| SCHEMBL9414951 | 0.90 | HSD17B10 (0.47) | POLBABCB1RAB9AMEN1KMT2A | |
| SCHEMBL9414954 | 0.90 | HSD17B10 (0.47) | POLBABCB1RAB9AMEN1KMT2A | |
| SCHEMBL9415558 | 0.90 | HSD17B10 (0.47) | POLBABCB1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589039-A1 | TRIPHENYLETHYLENE DERIVATIVE AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1994-03-30 | — | — | EP | disclosed |