Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9415486 | 1.00 | HSD17B10 (0.51) | HSD17B10POLBGAAABCB1ALDH1A1 | |
| SCHEMBL9415362 | 1.00 | HSD17B10 (0.51) | HSD17B10POLBGAAABCB1ALDH1A1 | |
| SCHEMBL9415369 | 1.00 | HSD17B10 (0.51) | HSD17B10POLBGAAABCB1ALDH1A1 | |
| SCHEMBL9415325 | 0.94 | HSD17B10 (0.50) | HSD17B10POLBGAAABCB1ESR1 | |
| SCHEMBL9415382 | 0.94 | HSD17B10 (0.50) | HSD17B10POLBGAAABCB1ESR1 | |
| SCHEMBL9415330 | 0.94 | HSD17B10 (0.50) | HSD17B10POLBGAAABCB1ESR1 | |
| SCHEMBL9415461 | 0.94 | HSD17B10 (0.50) | HSD17B10POLBGAAABCB1ALDH1A1 | |
| SCHEMBL9415179 | 0.94 | HSD17B10 (0.50) | HSD17B10POLBGAAABCB1ALDH1A1 | |
| SCHEMBL9415175 | 0.94 | HSD17B10 (0.50) | HSD17B10POLBGAAABCB1ALDH1A1 | |
| SCHEMBL9415376 | 0.94 | HSD17B10 (0.50) | HSD17B10POLBGAAABCB1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589039-A1 | TRIPHENYLETHYLENE DERIVATIVE AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1994-03-30 | — | — | EP | disclosed |