Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GRM8 | O00222 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9415843 | 1.00 | ANPEP (0.47) | ANPEPBTKTSHREPHX2SLC1A2 | |
| SCHEMBL9415840 | 1.00 | ANPEP (0.47) | ANPEPBTKTSHREPHX2SLC1A2 | |
| SCHEMBL9504406 | 0.85 | ANPEP (0.46) | ANPEPBTKTSHREPHX2SLC1A2 | |
| SCHEMBL9505565 | 0.85 | ANPEP (0.46) | ANPEPBTKTSHREPHX2SLC1A2 | |
| SCHEMBL9504417 | 0.85 | ANPEP (0.46) | ANPEPBTKTSHREPHX2SLC1A2 | |
| SCHEMBL14447179 | 0.81 | BTK (0.45) | ANPEPBTKTSHREPHX2GABRR1 | |
| SCHEMBL824192 | 0.81 | BTK (0.45) | ANPEPBTKTSHREPHX2GABRR1 | |
| SCHEMBL19604526 | 0.81 | BTK (0.45) | ANPEPBTKTSHREPHX2GABRR1 | |
| SCHEMBL12926820 | 0.78 | BTK (0.42) | ANPEPBTKTSHREPHX2SLC1A2 | |
| SCHEMBL3892778 | 0.75 | BTK (0.46) | ANPEPBTKTSHREPHX2SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618223-A2 | Peptides inhibiting interleukin 1-bêta release useful as antiinflammatory agents | SANDOZ LTD. (CH) | 1994-10-05 | — | — | EP | disclosed |