Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9415960 | 1.00 | KCNH2 (0.57) | KCNH2MAPTCARM1PRMT6PRMT8 | |
| SCHEMBL9415994 | 1.00 | KCNH2 (0.57) | KCNH2MAPTCARM1PRMT6PRMT8 | |
| SCHEMBL9415950 | 1.00 | KCNH2 (0.57) | KCNH2MAPTCARM1PRMT6PRMT8 | |
| SCHEMBL9415896 | 1.00 | KCNH2 (0.57) | KCNH2MAPTCARM1PRMT6PRMT8 | |
| SCHEMBL9005882 | 0.91 | KCNH2 (0.66) | KCNH2MAPTBCHEDRD2OPRM1 | |
| SCHEMBL11359571 | 0.91 | KCNH2 (0.66) | KCNH2MAPTBCHEDRD2OPRM1 | |
| SCHEMBL7606887 | 0.91 | KCNH2 (0.66) | KCNH2MAPTBCHEDRD2OPRM1 | |
| SCHEMBL9005868 | 0.91 | KCNH2 (0.66) | KCNH2MAPTBCHEDRD2OPRM1 | |
| SCHEMBL1262236 | 0.91 | KCNH2 (0.66) | KCNH2MAPTBCHEDRD2OPRM1 | |
| SCHEMBL1260761 | 0.91 | KCNH2 (0.66) | KCNH2MAPTBCHEDRD2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0599265-A1 | Antibacterial, antifungal compound and its production method | Takeda Chemical Industries, Ltd. (JP) | 1994-06-01 | — | — | EP | disclosed |