Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TOP2A | P11388 | 2/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416448 | 0.92 | MEN1 (0.35) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9146734 | 0.89 | KCNH2 (0.47) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9694860 | 0.86 | MEN1 (0.48) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9694375 | 0.84 | MEN1 (0.40) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9234517 | 0.82 | MEN1 (0.39) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9694117 | 0.82 | MEN1 (0.36) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9694116 | 0.82 | KDM4E (0.43) | KCNH2POLBMEN1KMT2ATOP2A | |
| SCHEMBL9416442 | 0.82 | POLB (0.34) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9145290 | 0.81 | MEN1 (0.47) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL7848981 | 0.79 | TOP2A (0.33) | KCNH2POLBMEN1KMT2ATOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607825-A1 | 6-H-4-OXO-3-quinoline-carboxylic acids and their analogues as antibacterial agents | BAYER AG (DE) | 1994-07-27 | — | — | EP | disclosed |