Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9144784 | 0.91 | EPHA2 (0.51) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL7850852 | 0.89 | EPHA2 (0.43) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL9416457 | 0.87 | EPHA2 (0.41) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL7854154 | 0.84 | EPHA2 (0.45) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| Hydrochloric Acid SCHEMBL9416482 | 0.84 | EPHA2 (0.47) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL8736066 | 0.83 | KCNH2 (0.36) | ALDH1A1POLB | |
| SCHEMBL9416452 | 0.83 | CYP3A4 (0.37) | CYP3A4 | |
| SCHEMBL9416445 | 0.83 | CYP3A4 (0.37) | CYP3A4 | |
| SCHEMBL9416497 | 0.82 | — | — | |
| SCHEMBL7850849 | 0.79 | EPHA2 (0.54) | EPHA2FLT4GSK3BRARBTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607825-A1 | 6-H-4-OXO-3-quinoline-carboxylic acids and their analogues as antibacterial agents | BAYER AG (DE) | 1994-07-27 | — | — | EP | disclosed |