Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.77 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA7 | P43166 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3048411 | 0.94 | MAPK1 (0.88) | MAPK1PDE4BLMNAMAPTPDE4D | |
| SCHEMBL3052857 | 0.89 | PDE4B (0.69) | MAPK1PDE4BLMNAMAPTPDE4D | |
| SCHEMBL3054722 | 0.88 | MAPK1 (0.65) | MAPK1PDE4BLMNAMAPTPDE4D | |
| SCHEMBL3056626 | 0.86 | PDE4B (0.71) | MAPK1PDE4BLMNAMAPTPDE4D | |
| SCHEMBL3057847 | 0.85 | MAPK1 (0.62) | MAPK1PDE4BLMNAMAPTPDE4D | |
| SCHEMBL18620486 | 0.82 | PDE4B (0.59) | MAPK1PDE4BLMNAMAPTPDE4D | |
| SCHEMBL3052611 | 0.81 | KDM4E (0.70) | MAPK1PDE4BLMNAMAPTCA1 | |
| SCHEMBL3504393 | 0.81 | MAPK1 (0.56) | MAPK1PDE4BMAPTCA1CA2 | |
| SCHEMBL9669207 | 0.81 | MAPK1 (0.56) | MAPK1PDE4BMAPTCA1CA2 | |
| SCHEMBL8793697 | 0.81 | MAPK1 (0.56) | MAPK1CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613879-A1 | PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1994-09-07 | — | — | EP | disclosed |