Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422157 | 0.86 | HTR2A (0.44) | ESR2CHRNB4CHRNA3ESR1HTR2A | |
| SCHEMBL6294315 | 0.78 | HTR2A (0.42) | ESR2CHRNB4CHRNA3ESR1HTR2A | |
| SCHEMBL6294296 | 0.78 | HTR2A (0.42) | ESR2CHRNB4CHRNA3ESR1HTR2A | |
| SCHEMBL6294297 | 0.78 | HTR2A (0.42) | ESR2CHRNB4CHRNA3ESR1HTR2A | |
| Hydrochloric Acid SCHEMBL6294327 | 0.77 | HTR2A (0.44) | ESR2CHRNB4CHRNA3ESR1HTR2A | |
| SCHEMBL9419090 | 0.75 | GRIN1 (0.52) | — | |
| SCHEMBL23923443 | 0.75 | HTR2A (0.56) | CHRNB4CHRNA3HTR2AHTR2CHTR2B | |
| SCHEMBL23923444 | 0.75 | HTR2A (0.56) | CHRNB4CHRNA3HTR2AHTR2CHTR2B | |
| SCHEMBL23923588 | 0.75 | HTR2A (0.56) | CHRNB4CHRNA3HTR2AHTR2CHTR2B | |
| SCHEMBL30317790 | 0.75 | HTR2A (0.56) | CHRNB4CHRNA3HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5367079-A | Lipoxygenase inhibitors; antiinflammatory agents, antiallergens | ZENECA LIMITED (GB) | 1994-11-22 | — | — | US | disclosed |
| EP-0570112-A1 | Cycloalkane derivatives | ZENECA LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |