SCHEMBL9419232

SCHEMBL9419232

O=C(O)c1c(Br)c(Br)c(C(=O)O)c(C(=O)O)c1Br

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.43
F2 P00734 3/20 0.39
PRSS1 P07477 3/20 0.39
PRSS2 P07478 3/20 0.39
PRSS3 P35030 3/20 0.39
PTPN1 P18031 1/20 0.35
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
CASP1 P29466 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1613627 0.93 F2 (0.43) CYP1A2F2PRSS1PRSS2PRSS3
SCHEMBL3475648 0.93 CYP1A2 (0.40) CYP1A2F2PRSS1PRSS2PRSS3
SCHEMBL7529954 0.93 CYP1A2 (0.40) CYP1A2F2PRSS1PRSS2PRSS3
SCHEMBL1035933 0.93 CYP1A2 (0.47) CYP1A2F2PRSS1PRSS2PRSS3
SCHEMBL35828 0.90 CYP1A2 (0.45) CYP1A2F2PRSS1PRSS2PRSS3
SCHEMBL588970 0.90 CYP1A2 (0.45) CYP1A2F2PRSS1PRSS2PRSS3
SCHEMBL29514787 0.90 CYP1A2 (0.45) CYP1A2F2PRSS1PRSS2PRSS3
Hydrochloric Acid SCHEMBL11258021 0.90 CYP1A2 (0.45) CYP1A2F2PRSS1PRSS2PRSS3
Hydrochloric Acid SCHEMBL11052779 0.90 CYP1A2 (0.38) CYP1A2F2PRSS1PRSS2PRSS3
Ammonia Solution, Strong SCHEMBL11581673 0.87 F2 (0.43) CYP1A2F2PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0326514-B1 Smoke and toxic gas suppressant composition FMC CORP UK LTD (GB) 1994-06-08 EP disclosed
EP-0549022-A2 Polymeric materials FMC CORPORATION (UK) LIMITED (GB) 1993-06-30 EP disclosed
US-4966920-A FOR POLYURETHANES; POLYESTER WITH LOW ACID VALUE MADE FROM COMPONENT HAVING FOUR CARBOXYL GROUPS CIBA-GEIGY CORPORATION (US) 1990-10-30 US disclosed
EP-0326514-A2 Smoke and toxic gas suppressant composition FMC CORPORATION (UK) LIMITED (GB) 1989-08-02 EP disclosed