Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18251006 | 0.99 | CYP1A2 (0.31) | ESR2 | |
| SCHEMBL29324436 | 0.96 | ESR2 (0.32) | ESR2 | |
| SCHEMBL8938802 | 0.95 | ESR2 (0.36) | ESR2 | |
| SCHEMBL9406033 | 0.93 | ESR2 (0.35) | ESR2 | |
| SCHEMBL9406214 | 0.92 | ESR2 (0.34) | ESR2 | |
| SCHEMBL9405795 | 0.92 | ESR2 (0.34) | ESR2 | |
| SCHEMBL9406182 | 0.92 | ESR2 (0.34) | ESR2 | |
| SCHEMBL9405941 | 0.89 | ESR2 (0.36) | ESR2 | |
| SCHEMBL13378094 | 0.89 | — | — | |
| SCHEMBL13378137 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363458-B1 | 2,3-DIFLUOROBENZENES | MERCK PATENT GMBH (DE) | 1994-08-03 | — | — | EP | disclosed |
| US-5087764-A | Deprotonation of a 1-substituted-2,3-difluorobenzene using an organometallic compound and reacting the reaction product with an electrophile | Merck Patent Gesellschaft mit beschrankter Hafung (DE) | 1992-02-11 | — | — | US | disclosed |