Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GGT1 | P19440 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9419438 | 0.98 | PPARG (0.59) | PPARGPPARAPTGS2KDM4EALDH1A1 | |
| SCHEMBL6996922 | 0.88 | CA12 (0.63) | PPARGPPARAPTGS2KDM4EALDH1A1 | |
| SCHEMBL28423316 | 0.81 | CA12 (0.55) | PPARGPPARATSHRCA12CA1 | |
| SCHEMBL9394952 | 0.81 | CA12 (0.78) | PPARGPPARAPTGS2KDM4EALDH1A1 | |
| SCHEMBL9712657 | 0.79 | KMT2A (0.57) | PPARGPPARAALDH1A1CA12CA1 | |
| SCHEMBL9393216 | 0.79 | CA12 (0.59) | PPARGPPARAPTGS2KDM4EALDH1A1 | |
| SCHEMBL23748636 | 0.78 | CA12 (0.66) | PPARATSHRCA12CA1CA2 | |
| SCHEMBL9419449 | 0.78 | MAPK1 (0.73) | PTGS2KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL9364224 | 0.77 | KDM4E (0.55) | PPARGPPARAPTGS2KDM4EALDH1A1 | |
| SCHEMBL1156927 | 0.77 | KDM4E (0.70) | PPARGPPARAPTGS2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580386-A1 | Aromatic polyanhydrides | ETHICON, INC. (US) | 1994-01-26 | — | — | EP | disclosed |
| US-5264540-A | Purification of acid monomer and anhydride prepolymer | ETHICON, INC. (US) | 1993-11-23 | — | — | US | disclosed |