SCHEMBL9419802

SCHEMBL9419802

CCCCCCCCCCCCCCCCCC(=O)NNC(=O)CCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.65

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.65
KMT2A Q03164 3/20 0.65
ALDH1A1 P00352 1/20 0.55
LMNA P02545 1/20 0.55
AGTR1 P30556 1/20 0.55
HTT P42858 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
MEN1 O00255 2/20 0.48
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
CNR2 P34972 7/20 0.46
CNR1 P21554 7/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39122 0.89 GAA (0.77) GAAKMT2AALDH1A1LMNAAGTR1
SCHEMBL11061451 0.88 GAA (0.64) GAAKMT2AALDH1A1LMNAAGTR1
SCHEMBL30732960 0.87 GAA (0.74) GAAKMT2AALDH1A1LMNAAGTR1
SCHEMBL9899067 0.85 GAA (0.80) GAAKMT2AALDH1A1SMN1; SMN2MEN1
SCHEMBL11707087 0.85 KMT2A (0.71) GAAKMT2ALMNASMN1; SMN2MEN1
SCHEMBL9898274 0.85 GAA (0.80) GAAKMT2AALDH1A1SMN1; SMN2MEN1
SCHEMBL9925783 0.85 GAA (0.80) GAAKMT2AALDH1A1SMN1; SMN2MEN1
SCHEMBL407840 0.85 GAA (0.80) GAAKMT2AALDH1A1SMN1; SMN2MEN1
SCHEMBL19634869 0.85 GAA (0.80) GAAKMT2AALDH1A1SMN1; SMN2MEN1
SCHEMBL9898391 0.85 GAA (0.80) GAAKMT2AALDH1A1SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0382559-B1 Polymer composition TONEN SEKIYUKAGAKU KK (JP) 1994-11-02 EP disclosed
EP-0443663-B1 Stabilised compositions based on polyamides and objects prepared therefrom SOLVAY (BE) 1994-08-24 EP disclosed
US-5216054-A Polyamide, polyolefin, carboxylic acid modified polyolefin, substituted hydrazine, hindered phenol, phosphite, thiodipropionate; aging resistance and resistance to copper-caused deterioration TONEN SEKIYUKAGAKU KABUSHIKI KAISHA (JP) 1993-06-01 US disclosed
US-5147935-A Mixture with triaryl phosphite, amide, and hydrazide SOLVAY S.A. (BE) 1992-09-15 US disclosed
EP-0443663-A1 Stabilised compositions based on polyamides and objects prepared therefrom SOLVAY (Société Anonyme) (BE) 1991-08-28 EP disclosed
EP-0382559-A2 Polymer composition Tonen Chemical Corporation (JP) 1990-08-16 EP disclosed
US-4052362-A N-CINNAMOYL-N'-ACYLHYDRAZINES UBE INDUSTRIES, LTD. (JA) 1977-10-04 US disclosed