Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.52 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9420555 | 1.00 | KMT2A (0.66) | KMT2AMEN1ATML3MBTL1MAPT | |
| SCHEMBL9420548 | 1.00 | KMT2A (0.66) | KMT2AMEN1ATML3MBTL1MAPT | |
| SCHEMBL813536 | 0.95 | KMT2A (0.71) | KMT2AMEN1ATML3MBTL1MAPT | |
| SCHEMBL10524262 | 0.94 | KMT2A (0.59) | KMT2AMEN1ATML3MBTL1MAPT | |
| SCHEMBL30704446 | 0.92 | MAPT (0.63) | KMT2AMEN1ATML3MBTL1MAPT | |
| SCHEMBL11569186 | 0.90 | ATM (0.60) | KMT2AMEN1ATML3MBTL1MAPT | |
| SCHEMBL11956796 | 0.89 | MEN1 (0.57) | KMT2AMEN1ATML3MBTL1MAPT | |
| SCHEMBL11956797 | 0.89 | MEN1 (0.58) | KMT2AMEN1ATML3MBTL1MAPT | |
| SCHEMBL13224188 | 0.89 | MEN1 (0.54) | KMT2AMEN1ATML3MBTL1MAPT | |
| SCHEMBL11309248 | 0.88 | MEN1 (0.68) | KMT2AMEN1ATML3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328585-B1 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | BIORESEARCH INC (US) | 1994-09-07 | — | — | EP | disclosed |
| EP-0328585-A4 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | — | 1991-06-05 | — | — | EP | disclosed |
| EP-0328585-A1 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | BIORESEARCH INC. (US) | 1989-08-23 | — | — | EP | disclosed |
| US-4829099-A | SURGERY, POLYISOCYANATES, POLYISOTHIOCYANATES | BIORESEARCH, INC. (US) | 1989-05-09 | — | — | US | disclosed |
| WO-1989000589-A1 | METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES | BIORESEARCH, INC. (US) | 1989-01-26 | — | — | WO | disclosed |
| US-4246392-A | Method for the preparation of polyurethane elastomers based on polyethyleneglycol-bis(4-aminobenzoates) | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1981-01-20 | — | — | US | disclosed |