⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660930 | 0.86 | TSHR (0.33) | — | |
| SCHEMBL28687343 | 0.79 | MEN1 (0.43) | — | |
| SCHEMBL10509707 | 0.78 | MEN1 (0.39) | — | |
| SCHEMBL9660403 | 0.76 | MEN1 (0.31) | — | |
| SCHEMBL29386019 | 0.73 | SLC5A1 (0.32) | — | |
| SCHEMBL28756067 | 0.73 | MEN1 (0.36) | — | |
| SCHEMBL9372095 | 0.72 | — | — | |
| SCHEMBL1950397 | 0.70 | — | — | |
| SCHEMBL13651840 | 0.69 | MEN1 (0.33) | — | |
| SCHEMBL30874137 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0120276-B1 | SUBSTITUTED DIAZOLYLALKYL OR TRIAZOLYLALKYL CARBINOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTIMYCOTIC COMPOUNDS | BAYER AG (DE) | 1986-10-15 | — | — | EP | claimed |
| US-5330976-A | Synergistic mixture | MILES INC. (US) | 1994-07-19 | — | — | US | disclosed |
| US-5194427-A | Synergistic | BAYER AG (DE) | 1993-03-16 | — | — | US | disclosed |
| US-5149795-A | Fungicides | BAYER AG (DE) | 1992-09-22 | — | — | US | disclosed |
| US-5134126-A | Antimycotic compositions of nikkomycin compounds and azole antimycotics | BAYER AG (DE) | 1992-07-28 | — | — | US | disclosed |
| US-5096889-A | Fungicides; synergistic | BAYER AG (DE) | 1992-03-17 | — | — | US | disclosed |
| US-5091375-A | Fungicides | BAYER AG (DE) | 1992-02-25 | — | — | US | disclosed |
| US-5019560-A | Method for treating fungal infections with nikkomycin derivatives | BAYER AG (DE) | 1991-05-28 | — | — | US | disclosed |
| US-5011850-A | Substituted diazolylalkyl-carbinols, a process for their preparation and their use as antimycotic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | disclosed |
| US-5006513-A | Fungicides, synergistic, itraconazole | MILES INC. (US) | 1991-04-09 | — | — | US | disclosed |
| US-4914087-A | FUNGICIDES | BAYER AG (DE) | 1990-04-03 | — | — | US | disclosed |
| EP-0315861-A1 | Antimycotic compositions of a nikkomycin compound and an antimycotic azole | BAYER AG (DE) | 1989-05-17 | — | — | EP | disclosed |
| EP-0131845-B1 | USE OF SUBSTITUTED DIAZOLYLALKYLCARBINOLS IN PLANT PROTECTION FOR THE CONTROL OF FUNGI | BAYER AG (DE) | 1987-09-02 | — | — | EP | disclosed |
| EP-0120276-B1 | SUBSTITUTED DIAZOLYLALKYL OR TRIAZOLYLALKYL CARBINOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTIMYCOTIC COMPOUNDS | BAYER AG (DE) | 1986-10-15 | — | — | EP | disclosed |
| EP-0131845-A2 | Use of substituted diazolylalkylcarbinols in plant protection for the control of fungi | BAYER AG (DE) | 1985-01-23 | — | — | EP | disclosed |
| EP-0120276-A1 | Substituted diazolylalkyl or triazolylalkyl carbinols, process for their preparation and their use as antimycotic compounds | BAYER AG (DE) | 1984-10-03 | — | — | EP | disclosed |