Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11559140 | 0.94 | TSHR (0.35) | TSHRLMNATHRB | |
| SCHEMBL14914312 | 0.86 | TSHR (0.39) | TSHRLMNATHRB | |
| SCHEMBL14915179 | 0.83 | TSHR (0.44) | TSHRLMNATHRB | |
| SCHEMBL14914216 | 0.72 | TSHR (0.32) | TSHRLMNATHRB | |
| SCHEMBL14915026 | 0.72 | — | — | |
| SCHEMBL14915766 | 0.71 | TSHR (0.35) | TSHRLMNATHRB | |
| Ethyne SCHEMBL9421962 | 0.69 | TSHR (0.40) | TSHRLMNATHRB | |
| SCHEMBL7321139 | 0.69 | TSHR (0.33) | TSHRLMNATHRB | |
| SCHEMBL4733739 | 0.69 | TSHR (0.33) | TSHRLMNATHRB | |
| Ethyne SCHEMBL9421998 | 0.67 | TSHR (0.38) | TSHRLMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286901-A | Prescursors for and synthesis of mono- and difunctionalized acetylenes and difunctional 1,3-diynes | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 1994-02-15 | — | — | US | disclosed |