⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Magnesium Chloride Anhydrous SCHEMBL22089878 | 0.87 | — | — | |
| SCHEMBL28901822 | 0.87 | — | — | |
| SCHEMBL5383115 | 0.74 | — | — | |
| SCHEMBL14715941 | 0.72 | — | — | |
| SCHEMBL385955 | 0.67 | — | — | |
| SCHEMBL11288411 | 0.67 | — | — | |
| SCHEMBL28239890 | 0.65 | — | — | |
| SCHEMBL1278191 | 0.65 | — | — | |
| SCHEMBL381096 | 0.64 | — | — | |
| SCHEMBL386419 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708321-B2 | Spiro-quinazolinone derivatives and their use as positive allosteric modulators of mGluR4 | MERCK PATENT GMBH (DE) | 2017-07-18 | — | — | US | claimed |
| US-20150361079-A1 | Spiro-Quinazolinone Derivatives and their Use as Positive Allosteric Modulators of mGluR4 | MERCK PATENT GMBH (DE) | 2015-12-17 | — | — | US | claimed |
| EP-2951179-A1 | SPIRO-QUINAZOLINONE DERIVATIVES USEFUL FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND CONDITIONS | Merck Patent GmbH (DE) | 2015-12-09 | — | — | EP | claimed |
| WO-2014117920-A1 | SPIRO-QUINAZOLINONE DERIVATIVES USEFUL FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND CONDITIONS | MERCK PATENT GMBH (DE) | 2014-08-07 | — | — | WO | claimed |
| WO-1994021274-A1 | SYNERGISTIC COMBINATION OF ETHAMBUTOL AND A GLYCOPEPTIDE ANTIBIOTIC | GRUPPO LEPETIT S.P.A. (IT) | 1994-09-29 | — | — | WO | claimed |
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
| US-9708321-B2 | Spiro-quinazolinone derivatives and their use as positive allosteric modulators of mGluR4 | MERCK PATENT GMBH (DE) | 2017-07-18 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| EP-3022199-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2016-05-25 | — | — | EP | disclosed |
| US-20150361079-A1 | Spiro-Quinazolinone Derivatives and their Use as Positive Allosteric Modulators of mGluR4 | MERCK PATENT GMBH (DE) | 2015-12-17 | — | — | US | disclosed |
| WO-2015008872-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-01-22 | — | — | WO | disclosed |
| WO-1994021274-A1 | SYNERGISTIC COMBINATION OF ETHAMBUTOL AND A GLYCOPEPTIDE ANTIBIOTIC | GRUPPO LEPETIT S.P.A. (IT) | 1994-09-29 | — | — | WO | disclosed |
| EP-0344660-B1 | THIOPHENE DERIVATIVES | BASF Aktiengesellschaft (DE) | 1992-07-22 | — | — | EP | disclosed |
| US-4937256-A | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1990-06-26 | — | — | US | disclosed |
| EP-0344660-A1 | Thiophene derivatives | BASF Aktiengesellschaft (DE) | 1989-12-06 | — | — | EP | disclosed |
| CN-88101000-A | The alkylamide of the replacement of teicoplanin compounds | — | 1988-09-14 | — | — | CN | disclosed |
| US-4026934-A | INSECTICIDES, ACARICIDES, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |