Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29210938 | 0.78 | POLA1 (0.43) | POLA1 | |
| SCHEMBL3102574 | 0.75 | POLA1 (0.35) | POLA1 | |
| SCHEMBL31070849 | 0.70 | POLA1 (0.30) | POLA1 | |
| SCHEMBL3431677 | 0.69 | — | — | |
| SCHEMBL2033847 | 0.69 | — | — | |
| SCHEMBL3458780 | 0.67 | KCNH2 (0.39) | — | |
| SCHEMBL9187292 | 0.65 | — | — | |
| SCHEMBL4240527 | 0.63 | — | — | |
| SCHEMBL3650233 | 0.62 | — | — | |
| SCHEMBL11528752 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318971-A | Also antihyperproliferative skin disease agents, e.g. psoriaisis; side effect reduction | SCHERING CORPORATION (US) | 1994-06-07 | — | — | US | disclosed |
| US-5064837-A | Antiallergens | SCHERING CORPORATION (US) | 1991-11-12 | — | — | US | disclosed |
| WO-1991007401-A1 | 3-SUBSTITUTED-1-(ARYL OR ARYLALKYL)-2(1H)-QUINOLINONES | SCHERING CORPORATION (US) | 1991-05-30 | — | — | WO | disclosed |