⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9424122 | 1.00 | — | — | |
| SCHEMBL9424114 | 0.83 | — | — | |
| SCHEMBL9424538 | 0.83 | — | — | |
| SCHEMBL9424112 | 0.83 | — | — | |
| SCHEMBL7059057 | 0.81 | — | — | |
| SCHEMBL9424245 | 0.81 | — | — | |
| SCHEMBL9424241 | 0.81 | — | — | |
| SCHEMBL9856554 | 0.80 | — | — | |
| SCHEMBL9424602 | 0.80 | — | — | |
| SCHEMBL9473099 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312828-A | Substituted imidazoles having angiotensin II receptor blocking activity | SMITHKLINE BEECHAM CORPORATION A CORP. OF PENNSYLVANIA | 1994-05-17 | — | — | US | disclosed |
| EP-0403158-A2 | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |