SCHEMBL9424337

SCHEMBL9424337

CCCCCCCCCc1ccc(C#Cc2cc(F)ccc2F)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.46
TSHR P16473 1/20 0.46
HTR2A P28223 1/20 0.45
RARB P10826 3/20 0.42
RARA P10276 1/20 0.42
RARG P13631 1/20 0.42
ESR1 P03372 2/20 0.41
ADRA2A P08913 2/20 0.41
ADORA3 P0DMS8 2/20 0.41
TACR2 P21452 2/20 0.41
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41
SLC6A3 Q01959 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
SHBG P04278 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
HSPD1 P10809 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9424772 1.00 HSD17B10 (0.46) HSD17B10TSHRHTR2ARARBRARA
SCHEMBL9424692 1.00 HSD17B10 (0.46) HSD17B10TSHRHTR2ARARBRARA
SCHEMBL9424696 1.00 HSD17B10 (0.46) HSD17B10TSHRHTR2ARARBRARA
SCHEMBL9424205 1.00 HSD17B10 (0.46) HSD17B10TSHRHTR2ARARBRARA
SCHEMBL9416292 0.99 HSD17B10 (0.43) HSD17B10TSHRHTR2ARARBRARA
SCHEMBL19403096 0.90 HSD17B10 (0.47) HSD17B10TSHRHTR2ARARBRARA
SCHEMBL8978789 0.88 HSD17B10 (0.50) HSD17B10TSHRHTR2ARARBRARA
SCHEMBL8979120 0.88 HSD17B10 (0.50) HSD17B10TSHRHTR2ARARBRARA
SCHEMBL8979108 0.88 HSD17B10 (0.50) HSD17B10TSHRHTR2ARARBRARA
SCHEMBL8979042 0.88 HSD17B10 (0.50) HSD17B10TSHRHTR2ARARBRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5356558-A Compatibility, high speed response SEIKO EPSON CORPORATION (JP) 1994-10-18 US disclosed