Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913053 | 1.00 | USP2 (0.44) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL7914513 | 1.00 | USP2 (0.44) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL9141627 | 0.88 | TSHR (0.46) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL9141624 | 0.88 | TSHR (0.46) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL9137453 | 0.88 | TSHR (0.46) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL7793977 | 0.86 | TSHR (0.45) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL7793979 | 0.86 | TSHR (0.45) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL7793974 | 0.86 | TSHR (0.45) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL7793981 | 0.85 | TSHR (0.43) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL9344125 | 0.85 | TSHR (0.43) | USP2TSHRKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5290477-A | Fluoroalkyl phenoxy containing pyrimidine-type compound | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1994-03-01 | — | — | US | disclosed |