Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL7684885 | 0.99 | GRM5 (0.54) | GRM5 | |
| SCHEMBL9424923 | 0.95 | GRM5 (0.50) | GRM5 | |
| Maleic Acid SCHEMBL7689292 | 0.89 | GRM5 (0.44) | GRM5 | |
| Water SCHEMBL7688869 | 0.81 | — | — | |
| SCHEMBL7678384 | 0.80 | GRM5 (0.51) | GRM5 | |
| Maleic Acid SCHEMBL7687399 | 0.78 | — | — | |
| SCHEMBL9424996 | 0.77 | KCNH2 (0.41) | — | |
| SCHEMBL7680381 | 0.76 | GRM5 (0.47) | GRM5 | |
| Water SCHEMBL7680601 | 0.76 | KCNH2 (0.41) | — | |
| SCHEMBL7685131 | 0.73 | GRM5 (0.50) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360811-A | 1-alkyl-, 1-alkenyl-, and 1-alkynylaryl-2-amino-1,3-propanediols and related compounds as anti-inflammatory agents | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-11-01 | — | — | US | claimed |