Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425232 | 0.89 | RXRB (0.45) | MAPTNPC1MEN1KMT2AGAA | |
| SCHEMBL9425916 | 0.84 | CA12 (0.34) | MAPTNPC1MEN1KMT2AGAA | |
| SCHEMBL16144926 | 0.81 | TSHR (0.44) | MAPTNPC1MEN1KMT2AGAA | |
| SCHEMBL9425798 | 0.81 | RXRB (0.50) | RXRB | |
| SCHEMBL15080878 | 0.76 | MAPT (0.52) | MAPTNPC1MEN1KMT2AGAA | |
| SCHEMBL9426101 | 0.76 | RARB (0.40) | NPC1CA12CA1CA2CA7 | |
| SCHEMBL4625676 | 0.74 | TSHR (0.56) | MAPTNPC1MEN1KMT2AGAA | |
| SCHEMBL164673 | 0.74 | TSHR (0.52) | MAPTNPC1MEN1KMT2AGAA | |
| SCHEMBL8866206 | 0.73 | HDAC3 (0.41) | MAPTNPC1MEN1KMT2AGAA | |
| SCHEMBL28743123 | 0.73 | TSHR (0.56) | MAPTNPC1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5349105-A | Skin disorder | ALLERGAN, INC. (US) | 1994-09-20 | — | — | US | disclosed |
| US-5202471-A | Skin disorders | ALLERGAN, INC. (US) | 1993-04-13 | — | — | US | disclosed |