Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | ATP4A | P20648 | 2/20 | 0.35 |
| ▸ | ATP4B | P51164 | 2/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 3/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8050474 | 0.99 | NR1H2 (0.36) | NR1H2NR1H3ATP4AATP4BPOLQ | |
| SCHEMBL8049772 | 0.93 | POLQ (0.36) | NR1H2NR1H3ATP4AATP4BPOLQ | |
| Hydrochloric Acid SCHEMBL8039444 | 0.92 | POLQ (0.35) | NR1H2NR1H3ATP4AATP4BPOLQ | |
| SCHEMBL8038767 | 0.89 | POLQ (0.37) | NR1H2NR1H3POLQKIF11CYP19A1 | |
| Hydrochloric Acid SCHEMBL8049814 | 0.87 | POLQ (0.37) | NR1H2NR1H3POLQKIF11CYP19A1 | |
| SCHEMBL8050077 | 0.85 | MAPT (0.33) | NR1H2NR1H3MAPTMAPK1NPSR1 | |
| SCHEMBL8056490 | 0.84 | POLQ (0.36) | NR1H2NR1H3ATP4AATP4BPOLQ | |
| Hydrochloric Acid SCHEMBL8056275 | 0.84 | MAPT (0.33) | MAPTMAPK1NPSR1LATS1LATS2 | |
| SCHEMBL8050015 | 0.83 | POLQ (0.35) | POLQKIF11SLC6A3CYP19A1CYP11B1 | |
| Hydrochloric Acid SCHEMBL8050511 | 0.83 | POLQ (0.35) | NR1H2NR1H3ATP4AATP4BPOLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328920-A | Alleviating memory dysfunctions | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-07-12 | — | — | US | disclosed |