Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | VDR | P11473 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3386292 | 1.00 | STAT3 (0.36) | STAT3CA12CA1CA9KMT2A | |
| SCHEMBL9426947 | 1.00 | STAT3 (0.36) | STAT3CA12CA1CA9KMT2A | |
| SCHEMBL5535445 | 0.88 | STAT3 (0.40) | STAT3CA12CA1CA9KMT2A | |
| SCHEMBL3807712 | 0.88 | STAT3 (0.40) | STAT3CA12CA1CA9KMT2A | |
| SCHEMBL3807715 | 0.88 | STAT3 (0.40) | STAT3CA12CA1CA9KMT2A | |
| SCHEMBL8960754 | 0.87 | KMT2A (0.39) | STAT3CA12CA1CA9KMT2A | |
| SCHEMBL8961169 | 0.87 | KMT2A (0.39) | STAT3CA12CA1CA9KMT2A | |
| SCHEMBL8960744 | 0.87 | KMT2A (0.39) | STAT3CA12CA1CA9KMT2A | |
| SCHEMBL23539439 | 0.86 | CA12 (0.39) | STAT3CA12CA1CA9KMT2A | |
| SCHEMBL1896971 | 0.86 | CA12 (0.39) | STAT3CA12CA1CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283346-A | Chemical intermediate for vitamin e | HOFFMANN-LA ROCHE INC. (US) | 1994-02-01 | — | — | US | claimed |
| US-5283346-A | Chemical intermediate for vitamin e | HOFFMANN-LA ROCHE INC. (US) | 1994-02-01 | — | — | US | disclosed |
| US-5232852-A | Enzymatic hydrolysis utilizing a lipase | HOFFMANN-LA ROCHE INC. (US) | 1993-08-03 | — | — | US | disclosed |