SCHEMBL9427

SCHEMBL9427

[CH2]C(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3287802 0.93
SCHEMBL5163608 0.83
SCHEMBL970350 0.77
SCHEMBL11395942 0.72
SCHEMBL19563 0.72
SCHEMBL7185155 0.72
SCHEMBL43027 0.72
SCHEMBL37676 0.72
SCHEMBL2474845 0.72
SCHEMBL7743795 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13974 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344315-A Preparation and application of trifluoro thioether (sulfoxide) aromatic amine derivative 顺毅股份有限公司 2024-07-16 CN claimed
WO-2024146383-A1 CYP11A1 INHIBITOR COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海闻耐医药科技有限公司 2024-07-11 WO claimed
CN-118307519-A CYP11A1 inhibitor compound, preparation method and application thereof 上海闻耐医药科技有限公司 2024-07-09 CN claimed
WO-2024131588-A1 N-SUBSTITUTED PHENYLPYRAZOLE DERIVATIVE, PREPARATION THEREFOR, AND USE THEREOF 顺毅股份有限公司 2024-06-27 WO claimed
CN-118221639-A N-substituted phenylpyrazole derivative and preparation and application thereof 顺毅股份有限公司 2024-06-21 CN claimed
CN-118159541-A Gonadotropin releasing hormone antagonist and preparation method and application thereof 山东绿叶制药有限公司 2024-06-07 CN claimed
CN-117327000-A Biphenyl tetrahydropyrrole compound and preparation method and application thereof 海南因瑞生物医药科技有限公司 2024-01-02 CN claimed
WO-2023237097-A1 19-NOR-C3,3-DISUBSTITUTED C21-AZACYCLO-SUBSTITUTED STEROID AND METHOD FOR USING SAME 山东绿叶制药有限公司 2023-12-14 WO claimed
CN-115232129-B PARP1 selective inhibitor and preparation method and application thereof 上海闻耐医药科技有限公司 2023-12-01 CN claimed
US-20230296983-A1 PHOTOSENSITIVE POLYMER, PHOTORESIST COMPOSITION INCLUDING THE SAME, AND METHOD OF FABRICATING SEMICONDUCTOR DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-09-21 US claimed
EP-0060697-A1 Heterocyclic derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-09-22 EP claimed
EP-0060094-A2 Guanidine derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-09-15 EP claimed
EP-0059597-A2 Guanidino-substituted heterocyclic derivatives having histamine H-2 antagonist activity IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-09-08 EP claimed
EP-0045155-A1 Guanidine derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-02-03 EP claimed
EP-0030092-A1 Guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-06-10 EP claimed
US-4249931-A 5-Oxy or thiomethyl substituted oxazolidine herbicide antidotes STAUFFER CHEMICAL COMPANY (US) 1981-02-10 US claimed
EP-0004747-A2 Processes for the preparation of oligomeric phosphates ester compositions STAUFFER CHEMICAL COMPANY (US) 1979-10-17 EP claimed
US-4168152-A TRIAZINE HERBICIDES WITH N-BENZENESULFONYL CARBAMATES AS HERBICIDE ANTIBOTES STAUFFER CHEMICAL COMPANY (US) 1979-09-18 US claimed
US-4111933-A PROTECTION OF FUNCTIONAL GROUPS DURING REACTION AND THEIR SUBSEQUENT RESTORATION BAYER AKTIENGESELLSCHAFT (DE) 1978-09-05 US claimed
US-4046801-A 13-Cis prostaglandin derivatives SYNTEX (U.S.A.) INC. (US) 1977-09-06 US claimed