Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.48 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPC | P11150 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 6/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364004 | 0.94 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1LPLLIPCFAAH | |
| SCHEMBL9364008 | 0.94 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1LPLLIPCFAAH | |
| SCHEMBL9363965 | 0.92 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1LPLLIPCFAAH | |
| SCHEMBL9363958 | 0.92 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1LPLLIPCFAAH | |
| SCHEMBL9856273 | 0.90 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1FAAHCES1 | |
| SCHEMBL9856343 | 0.88 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1FAAHCES1CYP4F2 | |
| SCHEMBL9363995 | 0.88 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1FAAHCES1 | |
| SCHEMBL9364859 | 0.83 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1LPLLIPCFAAH | |
| SCHEMBL9364855 | 0.83 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1LPLLIPCFAAH | |
| SCHEMBL9855528 | 0.83 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1FAAHLNPEPERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296732-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-09 | — | — | EP | claimed |
| EP-0296732-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1988-12-28 | — | — | EP | claimed |
| US-5314918-A | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0296732-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0403249-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |
| EP-0296732-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1988-12-28 | — | — | EP | disclosed |