⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84473 | 0.74 | — | — | |
| SCHEMBL83932 | 0.74 | — | — | |
| SCHEMBL15404168 | 0.71 | — | — | |
| SCHEMBL1469552 | 0.71 | — | — | |
| SCHEMBL477763 | 0.70 | — | — | |
| SCHEMBL477844 | 0.70 | — | — | |
| SCHEMBL10703783 | 0.70 | — | — | |
| SCHEMBL21875191 | 0.70 | — | — | |
| SCHEMBL1294256 | 0.70 | — | — | |
| SCHEMBL15167434 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8910 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12042495-B2 | MAP4K1 inhibitors | BLUEPRINT MEDICINES CORPORATION (US) | 2024-07-23 | — | — | US | claimed |
| US-20240228506-A1 | RIPK1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2024-07-11 | — | — | US | claimed |
| WO-2024146383-A1 | CYP11A1 INHIBITOR COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海闻耐医药科技有限公司 | 2024-07-11 | — | — | WO | claimed |
| CN-118307519-A | CYP11A1 inhibitor compound, preparation method and application thereof | 上海闻耐医药科技有限公司 | 2024-07-09 | — | — | CN | claimed |
| EP-4132650-B1 | DIFLUOROCYCLOHEXYL DERIVATIVES AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2024-06-12 | — | — | EP | claimed |
| EP-4380920-A1 | INHIBITORS FOR CORONAVIRUSES | Cocrystal Pharma, Inc. (US) | 2024-06-12 | — | — | EP | claimed |
| CN-118103351-A | Coronavirus inhibitors | 共晶制药公司 | 2024-05-28 | — | — | CN | claimed |
| CN-118063349-A | Cyclopropionamide substituted benzamide derivative and preparation method and application thereof | 山东省联合农药工业有限公司 | 2024-05-24 | — | — | CN | claimed |
| US-20240140915-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. | 2024-05-02 | — | — | US | claimed |
| CN-117903077-A | Dihydrooxadiazinon compound and application thereof | 上海超阳药业有限公司 | 2024-04-19 | — | — | CN | claimed |
| US-5393790-A | Diphenyl- or phenyl/pyridyl-substituted spiroheptenes, -octenes,-nonenes or -decenes; cyclooxygenase II inhibitors; side effect reduction; antipyretics; antiarthritic agents | G.D. SEARLE & CO. (US) | 1995-02-28 | — | — | US | claimed |
| EP-0398072-B1 | Amino-acid amides | BAYER AG (DE) | 1995-02-01 | — | — | EP | claimed |
| WO-1994027980-A1 | SUBSTITUTED OXAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1994-12-08 | — | — | WO | claimed |
| EP-0588105-A1 | Derivatives of Phosphoryloxypyrazole | BAYER AG (DE) | 1994-03-23 | — | — | EP | claimed |
| US-5210084-A | Amidoalkylcarbamates | BAYER AKTIENGESELLSCHAFT (DE) | 1993-05-11 | — | — | US | claimed |
| US-5169909-A | Method for the preparation of organopolysiloxane | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1992-12-08 | — | — | US | claimed |
| EP-0496239-A2 | Substituted aminoacid amide derivatives, their preparation and use as fungicide | BAYER AG (DE) | 1992-07-29 | — | — | EP | claimed |
| EP-0485794-A1 | Substituted aminoacid amide derivatives, their preparation and use | BAYER AG (DE) | 1992-05-20 | — | — | EP | claimed |
| EP-0398072-A2 | Amino-acid amides | BAYER AG (DE) | 1990-11-22 | — | — | EP | claimed |
| US-4840969-A | APPLYING AS INSECTICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | claimed |