SCHEMBL9429414

SCHEMBL9429414

CCCCCCCCON1C(C)(C)CC(CCCCNc2nc(NCCCCC3CC(C)(C)N(OCCCCCCCC)C(C)(C)C3)nc(N(COC)COC)n2)CC1(C)C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.32
EHMT2 Q96KQ7 3/20 0.31
EHMT1 Q9H9B1 3/20 0.31
DNM2 P50570 1/20 0.31
KCNH3 Q9ULD8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9429161 0.91 EHMT2 (0.32) KMT2AEHMT2EHMT1DNM2
SCHEMBL9428356 0.90 KMT2A (0.31) KMT2A
SCHEMBL9428020 0.88 SLC29A1 (0.43) KMT2ADNM2
SCHEMBL9429442 0.87
SCHEMBL9427949 0.85
SCHEMBL9428703 0.84 KMT2A (0.49) KMT2AEHMT2EHMT1DNM2KCNH3
SCHEMBL9428099 0.84 KMT2A (0.36) KMT2AEHMT2EHMT1DNM2KCNH3
SCHEMBL7456211 0.84 KMT2A (0.49) KMT2AEHMT2EHMT1DNM2KCNH3
SCHEMBL9428534 0.84 KMT2A (0.36) KMT2AEHMT2EHMT1DNM2KCNH3
SCHEMBL9428796 0.84 KMT2A (0.36) KMT2AEHMT2EHMT1DNM2KCNH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300544-A Non-migrating 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperdine 1,3,5-triazine derivatives as polymer stabilizers CIBA-GEIGY CORPORATION (US) 1994-04-05 US disclosed
US-5216156-A Stabilizers having functional groups which chemically bond with polymer substrates CIBA-GEIGY CORPORATION (US) 1993-06-01 US disclosed