Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 12/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.60 |
| ▸ | MAOA | P21397 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312844 | 0.78 | HPGD (0.67) | HPGDPTPN1MAOAMAOBPOLB | |
| SCHEMBL9312409 | 0.77 | PPARG (0.53) | HPGD | |
| SCHEMBL934311 | 0.76 | HPGD (1.00) | HPGDPTPN1MAOAMAOBPOLB | |
| SCHEMBL934310 | 0.76 | HPGD (1.00) | HPGDPTPN1MAOAMAOBPOLB | |
| SCHEMBL15421510 | 0.76 | HPGD (1.00) | HPGDPTPN1MAOAMAOBPOLB | |
| SCHEMBL1300345 | 0.74 | HPGD (1.00) | HPGDPTPN1MAOAMAOBPOLB | |
| SCHEMBL6866778 | 0.74 | HPGD (1.00) | HPGDPTPN1MAOAMAOBPOLB | |
| SCHEMBL1300347 | 0.74 | HPGD (1.00) | HPGDPTPN1MAOAMAOBPOLB | |
| SCHEMBL9326177 | 0.73 | HPGD (0.80) | HPGDPTPN1MAOAMAOBPOLB | |
| SCHEMBL9326976 | 0.73 | HPGD (0.80) | HPGDPTPN1MAOAMAOBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5330999-A | Diabetes, obesity | ADIR ET COMPAGNIE (FR) | 1994-07-19 | — | — | US | disclosed |
| US-5266582-A | Antidiabetic agents | ADIR ET COMPAGNIE (FR) | 1993-11-30 | — | — | US | disclosed |
| EP-0528734-A1 | Thiazolidin-2,4-dione derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-02-24 | — | — | EP | disclosed |