Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 14/20 | 0.67 |
| ▸ | CYSLTR1 | Q9Y271 | 14/20 | 0.67 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503905 | 1.00 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1LPAR1 | |
| SCHEMBL8925768 | 0.93 | CYSLTR2 (0.78) | CYSLTR2CYSLTR1 | |
| SCHEMBL9357210 | 0.91 | CYSLTR2 (0.66) | CYSLTR2CYSLTR1 | |
| SCHEMBL9559947 | 0.91 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1 | |
| SCHEMBL9560059 | 0.89 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1 | |
| SCHEMBL9356898 | 0.88 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1 | |
| SCHEMBL9561489 | 0.86 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1 | |
| SCHEMBL9561427 | 0.86 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1 | |
| SCHEMBL9560002 | 0.86 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1 | |
| SCHEMBL9428284 | 0.85 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314918-A | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0296732-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0403249-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |
| EP-0296732-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1988-12-28 | — | — | EP | disclosed |