SCHEMBL9430385

SCHEMBL9430385

Oc1ccc2cc3cc4ccccc4cc3cc2c1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN22 Q9Y2R2 1/20 0.61
ALOX5 P09917 2/20 0.46
TRPM4 Q8TD43 1/20 0.45
ALDH1A1 P00352 4/20 0.44
HSD17B10 Q99714 3/20 0.44
HIF1A Q16665 2/20 0.44
CYP1B1 Q16678 1/20 0.44
NQO2 P16083 1/20 0.43
CYP1A2 P05177 2/20 0.43
POLB P06746 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
NPC1 O15118 1/20 0.42
HSP90AA1 P07900 1/20 0.42
RAB9A P51151 1/20 0.42
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
HBB P68871 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27685067 1.00 PTPN22 (0.61) PTPN22ALOX5TRPM4ALDH1A1HSD17B10
SCHEMBL28752695 1.00 PTPN22 (0.61) PTPN22ALOX5TRPM4ALDH1A1HSD17B10
SCHEMBL29447273 0.98 PTPN22 (0.64) PTPN22ALOX5TRPM4ALDH1A1HSD17B10
SCHEMBL25429187 0.98 PTPN22 (0.64) PTPN22ALOX5TRPM4ALDH1A1HSD17B10
SCHEMBL82870 0.98 PTPN22 (0.64) PTPN22ALOX5TRPM4ALDH1A1HSD17B10
SCHEMBL14152971 0.96 PTPN22 (0.61) PTPN22ALOX5TRPM4ALDH1A1HSD17B10
SCHEMBL14152970 0.96 PTPN22 (0.61) PTPN22ALOX5TRPM4ALDH1A1HSD17B10
SCHEMBL10583732 0.90 PTPN22 (0.55) PTPN22ALOX5ALDH1A1HSD17B10CYP1A2
Phenol SCHEMBL27621492 0.90 PTPN22 (0.55) PTPN22ALOX5TRPM4ALDH1A1HSD17B10
SCHEMBL14841344 0.88 PTPN22 (0.53) PTPN22ALOX5TRPM4ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115461388-A Thermoplastic resin and optical component 帝人株式会社 2022-12-09 CN disclosed
CN-104000781-B Amrubicin liposome and its preparation method CHONGQING SHENGHUAXI PHARMACEUTICAL CO., LTD. (CN) 2016-06-01 CN disclosed
CN-104000781-A Anthracycline liposome and preparing method thereof CHONGQING SHENGHUAXI PHARMA CO 2014-08-27 CN disclosed
CN-101732333-B Medicament for treating cancer DAINIPPON SUMITOMO PHARMA CO 2012-08-15 CN disclosed
CN-101185652-B Remedies for lung cancer DAINIPPON SUMITOMO PHARMA CO 2010-12-08 CN disclosed
CN-101732333-A Medicament for treating cancer DAINIPPON SUMITOMO PHARMA CO 2010-06-16 CN disclosed
CN-100581585-C Cancer therapeutic agent SUMITOMO PHARMA 2010-01-20 CN disclosed
CN-100400046-C Therapeutic agent for lung cancer SUMITOMO PHARMA (JP) 2008-07-09 CN disclosed
CN-101185652-A Remedies for lung cancer SUMITOMO PHARMA (JP) 2008-05-28 CN disclosed
CN-1857723-A Slow released anticancer medicine preparation with both amrubicin and its synergist KANGQUAN MEDICINE SCI TECH CO (CN) 2006-11-08 CN disclosed
CN-1857216-A Slow released injection containing satraplatin and its synergist KANGQUAN MEDICINE SCI TECH CO (CN) 2006-11-08 CN disclosed
CN-1652800-A Therapeutic agent for lung cancer SUMITOMO PHARMA (JP) 2005-08-10 CN disclosed
CN-1466464-A Cancer therapeutic agent ס����ҩ��ʽ���� 2004-01-07 CN disclosed
US-5338863-A Catalytic sulfiding CIBA-GEIGY CORPORATION (US) 1994-08-16 US disclosed
US-5206390-A Intermediates for tetrathiotetracenes CIBA-GEIGY CORPORATION (US) 1993-04-27 US disclosed
EP-0344112-B1 SUBSTITUTED BISACYLOXYNAPHTHACENES, AND PROCESS FOR THE PREPARATION OF TETRATHIOTETRACENES CIBA-GEIGY AG (CH) 1993-01-20 EP disclosed
EP-0344112-A2 Substituted bisacyloxynaphthacenes, and process for the preparation of tetrathiotetracenes CIBA-GEIGY AG (CH) 1989-11-29 EP disclosed