⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5155451 | 0.77 | — | — | |
| SCHEMBL13844956 | 0.77 | — | — | |
| SCHEMBL256677 | 0.77 | — | — | |
| SCHEMBL29957485 | 0.75 | KDM1A (0.39) | — | |
| SCHEMBL2026442 | 0.75 | — | — | |
| SCHEMBL6256634 | 0.75 | — | — | |
| SCHEMBL9816683 | 0.75 | KDM1A (0.36) | — | |
| SCHEMBL4795813 | 0.75 | — | — | |
| SCHEMBL155344 | 0.75 | — | — | |
| SCHEMBL19248841 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122028913-A | Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions | 阿达尔克斯制药有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-116286817-B | Nucleic acid aptamer for targeting p53-R175H, protein targeting degradation chimeric body and application thereof | 山东师范大学 | 2025-05-02 | — | — | CN | disclosed |
| US-20250082768-A1 | CONJUGATING REAGENTS AND CONJUGATES THEREOF | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2025-03-13 | — | — | US | disclosed |
| CN-116179554-B | Conditional protein targeted degradation chimeric based on nucleic acid aptamer, and preparation method and application thereof | 山东师范大学 | 2025-03-04 | — | — | CN | disclosed |
| WO-2025038971-A1 | OLIGONUCLEOTIDES CONTAINING A LIGAND AT A NUCLEOBASE, 2' POSITION, OR 3' POSITION | ADARX PHARMACEUTICALS, INC. (US) | 2025-02-20 | — | — | WO | disclosed |
| CN-117750982-A | Coupling reagent and conjugate thereof | 剑桥实业有限公司 | 2024-03-22 | — | — | CN | disclosed |
| US-20240083934-A1 | N-ACETYLGALACTOSAMINE (GALNAC)-DERIVED COMPOUNDS AND OLIGONUCLEOTIDES | ADARX PHARMACEUTICALS, INC. (US) | 2024-03-14 | — | — | US | disclosed |
| EP-4225322-A1 | N-ACETYLGALACTOSAMINE(GALNAC)-DERIVED COMPOUNDS AND OLIGONUCLEOTIDES | Adarx Pharmaceuticals, Inc. (US) | 2023-08-16 | — | — | EP | disclosed |
| CN-116546989-A | N-acetylgalactosamine (GalNAc) derived compounds and oligonucleotides | 阿达尔克斯制药有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-116286817-A | Nucleic acid aptamer for targeting p53-R175H, protein targeting degradation chimeric body and application thereof | 山东师范大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-101535334-A | Method of covalently linking a carbohydrate or polyalkylene oxide to a peptide, precursors for use in the method and resultant products | UCL BUSINESS PLC (GB) | 2009-09-16 | — | — | CN | disclosed |
| US-20090227691-A1 | METHOD FOR RELEASING MOLECULE OF INTEREST BASED ON TARGET NUCLEIC ACID SEQUENCE | RIKEN (JP) | 2009-09-10 | — | — | US | disclosed |
| US-20090196829-A1 | MRI CONTRAST AGENTS AND RELATED METHODS OF USE | NORTHWESTERN UNIVERSITY (US) | 2009-08-06 | — | — | US | disclosed |
| EP-2046810-A2 | METHOD OF COVALENTLY LINKING A CARBOHYDRATE OR POLYALKYLENE OXIDE TO A PEPTIDE, PRECURSORS FOR USE IN THE METHOD AND RESULTANT PRODUCTS. | UCL Business PLC (GB) | 2009-04-15 | — | — | EP | disclosed |
| US-20090010846-A1 | Nitro-Imidazole Hypoxia Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2009-01-08 | — | — | US | disclosed |
| US-20090010846-A1 | Nitro-Imidazole Hypoxia Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2009-01-08 | — | — | US | disclosed |
| WO-2008124651-A2 | NITRO-IMIDAZOLE HYPOXIA IMAGING AGENTS | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2008-10-16 | — | — | WO | disclosed |
| WO-2008124651-A2 | NITRO-IMIDAZOLE HYPOXIA IMAGING AGENTS | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2008-10-16 | — | — | WO | disclosed |
| WO-2008001109-A2 | METHOD OF COVALENTLY LINKING A CARBOHYDRATE OR POLYALKYLENE OXIDE TO A PEPTIDE, PRECURSORS FOR USE IN THE METHOD AND RESULTANT PRODUCTS | UCL BUSINESS PLC (GB) | 2008-01-03 | — | — | WO | disclosed |
| WO-2008001109-A2 | METHOD OF COVALENTLY LINKING A CARBOHYDRATE OR POLYALKYLENE OXIDE TO A PEPTIDE, PRECURSORS FOR USE IN THE METHOD AND RESULTANT PRODUCTS | UCL BUSINESS PLC (GB) | 2008-01-03 | — | — | WO | disclosed |