Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.77 |
| ▸ | PPARA | Q07869 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914542 | 0.87 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL2786618 | 0.87 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL2786495 | 0.86 | PPARG (0.84) | PPARGPPARA | |
| SCHEMBL2786976 | 0.85 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL7922711 | 0.85 | PPARG (0.80) | PPARGPPARA | |
| SCHEMBL9086967 | 0.85 | PPARG (0.80) | PPARGPPARA | |
| SCHEMBL9086937 | 0.85 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL7922721 | 0.85 | PPARG (0.80) | PPARGPPARA | |
| SCHEMBL9086989 | 0.85 | PPARG (0.80) | PPARGPPARA | |
| SCHEMBL2786747 | 0.85 | PPARG (1.00) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994029285-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SMITHKLINE BEECHAM P.L.C. (GB) | 1994-12-22 | — | — | WO | claimed |
| WO-1994029285-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SMITHKLINE BEECHAM P.L.C. (GB) | 1994-12-22 | — | — | WO | disclosed |