Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9431351 | 0.94 | HMGCR (0.50) | HMGCRKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL581260 | 0.89 | HMGCR (0.44) | HMGCRKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL9431242 | 0.89 | HMGCR (0.46) | HMGCRKMT2AGAA | |
| SCHEMBL9431158 | 0.89 | HMGCR (0.46) | HMGCRKMT2AGAA | |
| Ethylene SCHEMBL14889349 | 0.84 | HMGCR (0.51) | HMGCRKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL3938564 | 0.84 | HMGCR (0.40) | HMGCRKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL284478 | 0.84 | CYP19A1 (0.43) | HMGCRKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL284526 | 0.84 | CYP19A1 (0.43) | HMGCRKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL284267 | 0.84 | CYP19A1 (0.43) | HMGCRKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL283561 | 0.84 | CYP19A1 (0.43) | HMGCRKMT2AALDH1A1MEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354486-A | A lubricant mixture consisting of 4-isopropionic acid or alky ester phenol; oxidation, radiation and heat resistance, nondeforming | CIBA-GEIGY CORPORATION (US) | 1994-10-11 | — | — | US | disclosed |
| US-5194607-A | REACTIVE DYES WITH A TRIPHENDIOXAZINE CHROMOPHORE | BASF AKTIENGESELLSCHAFT (DE) | 1993-03-16 | — | — | US | disclosed |