Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 6/20 | 0.61 |
| ▸ | CACNA1C | Q13936 | 10/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.58 |
| ▸ | MLNR | O43193 | 1/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.58 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 8/20 | 0.49 |
| ▸ | CACNA1D | Q01668 | 8/20 | 0.49 |
| ▸ | CACNA1S | Q13698 | 8/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401562 | 0.92 | CACNA1B (0.68) | CACNA1BCACNA1CADORA3MEN1KMT2A | |
| SCHEMBL9401960 | 0.92 | CACNA1B (0.72) | CACNA1BCACNA1CADORA3MEN1KMT2A | |
| SCHEMBL9401977 | 0.90 | CACNA1B (0.65) | CACNA1BCACNA1CADORA3MEN1KMT2A | |
| SCHEMBL9433371 | 0.90 | CACNA1B (0.52) | CACNA1BCACNA1CADORA3MEN1KMT2A | |
| SCHEMBL7291874 | 0.90 | CACNA1B (0.74) | CACNA1BCACNA1CADORA3MEN1KMT2A | |
| SCHEMBL7291542 | 0.90 | CACNA1B (0.64) | CACNA1BCACNA1CADORA3MEN1KMT2A | |
| SCHEMBL9433846 | 0.89 | CACNA1B (0.76) | CACNA1BCACNA1CADORA3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9401862 | 0.89 | CACNA1B (0.73) | CACNA1BCACNA1CADORA3MEN1KMT2A | |
| SCHEMBL9434467 | 0.89 | CACNA1B (0.53) | CACNA1BCACNA1CADORA3MEN1KMT2A | |
| SCHEMBL9433897 | 0.88 | CACNA1B (0.52) | CACNA1BCACNA1CADORA3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |