SCHEMBL9433770

SCHEMBL9433770

CCCCCCCCCOC(=O)C=C(C)N

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.56
ATM Q13315 1/20 0.52
TSHR P16473 4/20 0.50
NAAA Q02083 1/20 0.50
HPGD P15428 1/20 0.48
NPSR1 Q6W5P4 2/20 0.47
MAPT P10636 2/20 0.47
RAB9A P51151 2/20 0.47
EPHX1 P07099 1/20 0.47
ALDH1A1 P00352 3/20 0.45
HTR2C P28335 1/20 0.45
CES2 O00748 1/20 0.44
PRSS1 P07477 1/20 0.44
PRSS2 P07478 1/20 0.44
PRSS3 P35030 1/20 0.44
CYP3A4 P08684 1/20 0.44
RAD52 P43351 1/20 0.43
NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9434050 1.00 HCAR2 (0.56) HCAR2ATMTSHRNAAAHPGD
SCHEMBL10902247 1.00 HCAR2 (0.56) HCAR2ATMTSHRNAAAHPGD
SCHEMBL10543217 1.00 HCAR2 (0.56) HCAR2ATMTSHRNAAAHPGD
SCHEMBL9434472 1.00 HCAR2 (0.56) HCAR2ATMTSHRNAAAHPGD
SCHEMBL10902234 1.00 HCAR2 (0.56) HCAR2ATMTSHRNAAAHPGD
SCHEMBL10898563 1.00 HCAR2 (0.56) HCAR2ATMTSHRNAAAHPGD
SCHEMBL9433613 1.00 HCAR2 (0.56) HCAR2ATMTSHRNAAAHPGD
SCHEMBL10925831 1.00 HCAR2 (0.56) HCAR2ATMTSHRNAAAHPGD
SCHEMBL9434488 1.00 HCAR2 (0.56) HCAR2ATMTSHRNAAAHPGD
SCHEMBL9434037 1.00 HCAR2 (0.56) HCAR2ATMTSHRNAAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5276150-A Vasodilators, anticoagulants, calcium channel blockers FUJIREBIO INC. (JP) 1994-01-04 US disclosed
EP-0400660-A1 1,4-dihydropyridine derivatives FUJIREBIO INC. (JP) 1990-12-05 EP disclosed