Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.59 |
| ▸ | CASP1 | P29466 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | CASP7 | P55210 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434000 | 0.88 | CACNA1B (0.51) | KDM4EHSD17B10CASP1HPGDCASP7 | |
| SCHEMBL9434343 | 0.84 | KDM4E (0.64) | KDM4EHSD17B10CASP1HPGDCASP7 | |
| SCHEMBL9434114 | 0.83 | KDM4E (0.81) | KDM4EHSD17B10CASP1HPGDCASP7 | |
| SCHEMBL10432694 | 0.83 | HSD17B10 (0.65) | KDM4EHSD17B10CASP1HPGDCASP7 | |
| SCHEMBL9434538 | 0.83 | KDM4E (0.61) | KDM4EHSD17B10CASP1HPGDCASP7 | |
| SCHEMBL9433668 | 0.83 | HSD17B10 (0.61) | KDM4EHSD17B10CASP1HPGDCASP7 | |
| SCHEMBL9434728 | 0.83 | KDM4E (0.61) | KDM4EHSD17B10CASP1HPGDCASP7 | |
| SCHEMBL9434370 | 0.82 | KDM4E (0.60) | KDM4EHSD17B10CASP1HPGDCASP7 | |
| SCHEMBL10432260 | 0.82 | HSD17B10 (0.60) | KDM4EHSD17B10CASP1HPGDCASP7 | |
| SCHEMBL9433723 | 0.82 | KDM4E (0.63) | KDM4EHSD17B10CASP1HPGDCASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |