Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1C | Q14123 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | CACNA1C | Q13936 | 9/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 8/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 8/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 8/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433953 | 0.94 | PDE1C (0.49) | PDE1CCACNA1BCACNA1CCACNA1FCACNA1D | |
| SCHEMBL9433338 | 0.90 | MAPT (0.59) | PDE1CCACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL9434766 | 0.86 | CACNA1B (0.49) | PDE1CCACNA1BCACNA1CCACNA1FCACNA1D | |
| SCHEMBL9434232 | 0.85 | MAPT (0.59) | PDE1CCACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL9434220 | 0.83 | CACNA1B (0.51) | PDE1CCACNA1BCACNA1CCACNA1FCACNA1D | |
| SCHEMBL9434256 | 0.83 | CACNA1F (0.52) | PDE1CCACNA1BCACNA1CCACNA1FCACNA1D | |
| SCHEMBL9433634 | 0.82 | CACNA1F (0.55) | PDE1CCACNA1BCACNA1CCACNA1FCACNA1D | |
| SCHEMBL9434327 | 0.82 | CACNA1F (0.51) | PDE1CCACNA1BCACNA1CCACNA1FCACNA1D | |
| SCHEMBL9433733 | 0.82 | CACNA1B (0.55) | PDE1CCACNA1BCACNA1CCACNA1FCACNA1D | |
| SCHEMBL9434698 | 0.81 | CACNA1F (0.50) | PDE1CCACNA1BCACNA1CCACNA1FCACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |