Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 3/20 | 0.56 |
| ▸ | CACNA1C | Q13936 | 9/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | MLNR | O43193 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.54 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.51 |
| ▸ | CACNA1F | O60840 | 8/20 | 0.50 |
| ▸ | CACNA1D | Q01668 | 8/20 | 0.50 |
| ▸ | CACNA1S | Q13698 | 8/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434843 | 0.88 | CACNA1B (0.73) | CACNA1BCACNA1CMEN1KMT2AADORA3 | |
| SCHEMBL9434576 | 0.88 | PDE1C (0.54) | CACNA1BCACNA1CMEN1KMT2AADORA3 | |
| SCHEMBL9433835 | 0.88 | CACNA1B (0.73) | CACNA1BCACNA1CMEN1KMT2AADORA3 | |
| SCHEMBL9434328 | 0.87 | CACNA1B (0.57) | CACNA1BCACNA1CMEN1KMT2AADORA3 | |
| SCHEMBL9433317 | 0.85 | CACNA1B (0.66) | CACNA1BCACNA1CMEN1KMT2AADORA3 | |
| SCHEMBL9434424 | 0.85 | PDE1C (0.52) | CACNA1BCACNA1CMEN1KMT2AADORA3 | |
| SCHEMBL9434453 | 0.85 | CACNA1B (0.56) | CACNA1BCACNA1CMEN1KMT2AADORA3 | |
| SCHEMBL9434584 | 0.85 | CACNA1C (0.58) | CACNA1BCACNA1CMEN1KMT2AADORA3 | |
| SCHEMBL9433883 | 0.84 | CACNA1F (0.71) | CACNA1CMEN1KMT2AADORA3PDE1C | |
| SCHEMBL9434040 | 0.83 | CACNA1C (0.60) | CACNA1BCACNA1CMEN1KMT2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |